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* Bosentan because liver problems may occur; the effectiveness of both medicines may be decreased
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Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
Before giving Simplicef, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), probenecid, a loop diuretic such as furosemide, or warfarin. You may need to have the dosage adjusted. Drugs other than those listed here may also interact with Simplicef. Talk to your veterinarian or pharmacist before giving any prescription or Purchase Simplicef Rx OTC medicines, including vitamins, minerals, and herbal products.
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